Current UK Biobank projects involving UoM researchers

The lists below provides details of current research projects where colleagues from the University are either Principal Investigator (PI) or Lead, in collaboration with another institution.

You can also click through to read the abstract for each project on UK Biobank's website.

If you would like your study to be featured on this page, please email Natalie.Theodoulou@manchester.ac.uk (Research Development and Innovation Manager).

Researchers within the School of Biological Sciences

Title	Name	Duration in months / End Date	Link to Abstract on UK Biobank website
Development of a Frailty Index using Standard Laboratory Tests and its Utility in Predicting Adverse Health Outcomes	Faisal Hakeem	36 / 20/05/2025	View abstract
Leveraging large genome sequencing datasets to enhance the interpretation of rare genomic variants in developmental disorders	Alexander Blakes	36 / 16/12/2025	View abstract
Understanding the impact of rare DNA variants in molecular phenotypes & ophthalmic disease risk	Panagiotis Sergouniotis	72 / 01/04/2026	View abstract
Chronic High Impact Pain and UK Biobank: presentation, transitions, and targets for intervention (CHIPP)	John McBeth (Lead)	36 / 19/07/2026	View abstract
Harnessing the power of diverse populations to empower clinical translation of genome-wide association studies of common human disease	Andrew Morris	36 / 06/12/2026	View abstract
Improving causal inference in rheumatic diseases research by integrating observational and genetic epidemiology	Sizheng Zhao	72 / 18/10/2027	View abstract
Understanding pathophysiology, multimorbidity, and treatment response in chronic inflammatory conditions	Andrew Morris	36 / 16/12/2027	View abstract
Immune-Mediated Inflammatory Diseases: An Underestimated Stroke Risk Factor	Kieron South	36 / 04/08/2028	View abstract

Researchers within the School of Health Sciences

Title	Name	Duration in months / End Date	Link to abstract on UK Biobank website
Advancing understanding of multi-morbidity in metabolic disease through innovation in statistical machine learning	David Jenkins	36 / 14/09/2025	View abstract
A novel integrated predictive model for pancreatic cancer in the UK Biobank cohort	Temin Ke	36 / 30/11/2025	View abstract
The Impact of Cerebrovascular Burden and Stress on White Matter Integrity and Cognitive Function, During Healthy Ageing	Katie Moran	45 / 10/12/2025	View abstract
Integrative analysis of risk factors with multiple health conditions associated with ageing	Xinzhu Yu	36 / 16/02/2026	View abstract
Comparing resting state networks in post-traumatic stress disorder (PTSD) in cannabis and non-cannabis users and healthy controls in UK Biobank sample	Arpan Dutta	36 / 06/03/2026	View abstract
Studying the relationship between fairness and generalisability to develop fairer clinical prediction modelling for lung cancer and diabetes prognosis	Jose Benitez-Aurioles	36 / 20/11/2026	View abstract
The Impact of Ageing on Resting State Network Lateralization and its influence on memory function	Daniela Montaldi	36 / 05/12/2026	View abstract
AUtomated Generation of Musculoskeletal phENotypes from the UK biobank exTended imaging study (AUGMENT Study)	Tim Cootes (Lead)	129 / 01/05/2027	View abstract
Understanding Noradrenergic Alterations Associated with Early Life Stress	Megan Sheppard	39 / 30/07/2027	View abstract
Decoding Multimorbidity: A Pathway to Personalised Prevention	Owen Tipping	36 / 03/10/2027	View abstract
Health inequalities, environment, and productivity gap in the UK	Doriane Mignon	36 / 15/10/2027	View abstract
Predicting the persistence of substance-dependent patients from structural and functional brain images	Xinyue Teng	36 / 05/11/2027	View abstract
Occupational Particle Exposure and Chronic Kidney disease (OPECK)	Martie van Tongeren (Lead)	36 / 04/12/2027	View abstract
CARDIOMARKER- Computational imaging phenomics in population cardiac MRI with automatic image quality assessment: benchmarking, scalability and inference with state-of-the-art algorithms	Alejandro Frangi	108 / 17/01/2028	View abstract
Decoding Multimorbidity: A Pathway to Personalised Prevention	Artitaya Lophatananon	36 / 04/02/2028	View abstract
Association between modifiable lifestyle factors and onset of multiple long term conditions, with a view to causality	Alexander Pate	36 / 04/03/2028	View abstract
The effect of obesity on cancer risk through insulin resistance and glucose control in Chinese and UK populations: a causal mediation analysis (DOC-C2 project)	David Jenkins	36 / 24/03/2028	View abstract
Investigating comorbidities with cardiovascular diseases and type-2 diabetes using Bayesian causal networks	Jingqi Zhu	36 / 05/04/2028	View abstract
Using Artificial Intelligence-informed activity profiling based on passively collected accelerometer data for informing personalised lifestyle medicine targets in people with Severe Mental Illness	Lamiece Hassan	36 / 22/04/2028	View abstract
Development of ethnicity stratified causal risk prediction models of dementia	Alexandra Baousi	36 / 23/06/2028	View abstract

Researchers within the School of Medical Sciences

Title	Name	Duration in months / End Date	Link to Abstract on UK Biobank website
Genetic, environmental and clinical determinants of blood pressure, kidney health and disease	Maciej Tomaszewski	72 / 4-Nov-2025	View abstract
Sleep and chronotype and their causal links with cardiometabolic and chronic inflammatory diseases	Martin Rutter	150 / 15-Sep-2027	View abstract
Understanding the heterogeneity of heart failure and improving risk stratification	Christopher Miller	36 / 15-Oct-2027	View abstract
Magnetic resonance quantified visceral adipose tissue, intra-hepatic fat and Cancer: risk cohort, matched-driver analysis and Mendelian randomization study within UK Biobank [Magna Carta project]	Lee Malcomson	36 / 5-Nov-2027	View abstract
Genome Wide Association Study for Rectal Prolapse	Matthew Davenport	36 / 19/06/2028	View abstract
Prognostic markers of cardiac arrhythmias and new onset heart failure	Mohammed Obeidat	36 / 21/07/2028	View abstract
Genetic and inflammatory predictors of adverse pregnancy outcomes despite aspirin use: a UK Biobank study focused on the COX-2 pathway	Zhiyong Zou	36 / 01/08/2028	View abstract
Using human genetic information to uncover molecular drivers of vascular complications in type 2 diabetes	Abigail Lay	36 / 05/08/2028	View abstract

Researchers primarily based in FSE

Title

Name

Duration in months / End Date

Link to Abstract on UK Biobank website

Identification of cost-effective biomarkers for Alzheimer's disease

Fumie Costen (FSE)

36 /

20/12/2025

View abstract

Explainable automated ECG interpretation for visualizing and predicting ECG features at risk of life-threatening arrhythmia and sudden cardiac death

Alaa Alahmadi (FSE Honorary)

36 /

04/12/2027

View abstract