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Exploring interventions to maintain and prolong healthy skin function for an ageing population. How does our skin change with age?


Ethics ref: 13599

IRAS: 315711

Study summary 

As skin ages, we see a decline in skin barrier function, which can leave elderly people vulnerable to skin damage. We believe that these changes may start to happen at different ages in men and women, and may be due to changes in the skin’s lipid profile.  

In this study, we plan to investigate how the skin lipids change as we age, by recruiting healthy male and female White Caucasian volunteers aged 30-69. We will examine the lipid composition of the skin, how it changes as we get older, and how it relates to the function of the skin barrier. 

Who can take part? 

Healthy White Caucasian men and women aged 30-69. 

What will the research involve? 

This study will involve completing an online questionnaire, and then a single visit to the study unit. During this visit you will have your skin health assessed (including measurements of pH, water loss, hydration, and elasticity), then we will use adhesive tape strips to sample the very top layer of your skin. We will also take two skin biopsies (6 mm diameter) from the buttock skin of some volunteers (this is optional). 

Where will the research take place? 

You will need to complete a questionnaire online and then attend a unit at Salford Royal Hospital. 


You will be reimbursed for your time and inconvenience. 

Contact details


If you are interested in finding out more, please contact

Lindsay Cotterell Tel: 07435 660437;