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Wellcome ISSF - past calls

See details of all individual awards funded by the University’s Wellcome ISSF between 2014 and 2017.

2014 - 2017 awards

Strategic awards in single cell research

Strategic awards to develop and implement new technologies or to pump-prime major externally funded applications (eg WT Investigator, Collaborative and Strategic Awards) exploiting our new state-of-the-art single cell facility.

Application deadline: CLOSED

Successful applications in 2014/15:

TitlePrincipal InvestigatorsAward value
Understanding heterogeneity of inflammasome signalling Gloria Lopez-Castejon, David Brough, Pawel Paszek £12,000
Single cell ATACseq and cancer cell heterogeneity Andy Sharrocks, Edward Britton and Magnus Rattray £12,000
Developing approaches to combine imaging and biomechanics in the Light Sheet Microscope Sarah Woolner, Georgina Stooke-Vaughan, Dave Spiller £8,960
Investigating the conservation of T-helper cell differentiation in zebrafish Adam Hurlstone £12,000
Understanding how noise dampening allows robust cell fate oscillator dynamics Chris Thompson £7,662
Investigating endocrine-resistant breast cancer stem cells at single cell level to improve targeting of signalling pathways Robert Clarke, Bruno Simoes £12,000
Changes in CD4+ gene expression in response to TNF stimulation at the single-cell level Anne Barton, Stephen Eyre, Pawel Paszek, Paul Martin, Kevin Couper £12,000
Analysis of immune cell migration in a complex in vivo environment Tom Millard £2,194
Identification of exclusive breast cancer stem cell markers at single cell resolution Charles Streuli, Ahmet Ucar, Robert Clarke £11,252
Pilot study into sub-populations of the human embryonic pancreatic progenitor cell pool Neil Hanley £12,000
Quantitative single cell transcriptomics with unique molecular identifiers Pawel Paszek, Andrew Hayes, Magnus Rattray £11,956
Analysing the glucocorticoid transcriptome in single cells David Ray, Laura Matthews £12,000
Defining the mechanisms that control pulmonary macrophage responsiveness to inflammatory mediators Andrew MacDonald, Freya Svedberg, Peter Cook £12,000
How does the cartilage-protective protein TSG-6 affect the chondrocyte transcriptome in OA? Caroline Milner, Tony Day £12,000
Immunophenotyping patients with rheumatoid arthritis using CyTOF Jane Worthington, Anne Barton, Soumya Raychaudhuri, Tracy Hussell, Ben Mulhearn, Sebastien Viatte. £11,576
How does ageing affect homeostasis in the marrow niche? Joe Swift, Hamish TJ Gilbert, John Grainger £11,260
Investigation of stem cell fate choice by single cell sequencing Hilary Ashe £12,000
Classifying single-cells in a model of complex tissue: comparing the performance of ATAC-seq and RNA-seq assays Magnus Rattray, Syed Murtuza Baker, Andrew Sharrocks £12,000
Understanding the heterogeneity of activated innate lymphoid cell functions Matthew Hepworth £12,000
Can pseudotime gene network reconstruction from single cell RNAseq data be used to determine how cell fate choices are made? Chris Thompson, Magnus Rattray £11,930
Immunophenotyping patients with rheumatoid arthritis using CyTOF (continuation award) Sebastien Viatte, Ben Mulhearn, Anne Barton, Tracy Hussell, Soumya Raychaudhuri £5,945
Evaluating heterogeneity in myeloid cell inflammatory response by single-cell RNA-seq Kate Wicks, Kimberly Mace £11,930
Immunophenotyping T-regs in Juvenile Idiopathic Arthritis using CyTOF Annie Yarwood, Steve Eyre, Wendy Thomson, Jane Worthington £11,960
Establishment of Cell Fate Heterogeneity in Vascular Development Shane Herbert £6,000
Single-cell dynamics of ATP secretion Mike White, Rok Krašovec £11,922
Development of molecular and computational tools for single cell segmentation and RNA quantitation during Drosophila embryonic development Matthew Ronshaugen £4,500
Understanding macrophage heterogeneity in the human gastrointestinal tract Mark Travis, John Grainger, Tovah Shaw, Aoife Kelly £12,000

Strategic awards in clinical and pre-clinical imaging research

Strategic awards to develop and implement new technologies or to pump-prime major externally funded applications (e.g. WT Investigator, Collaborative and Strategic Awards) exploiting our clinical and pre-clinical human and animal imaging facilities, including the new state-of-the-art MR-PET scanner.

Application deadline: CLOSED

Successful applications in 2016:

TitlePrincipal InvestigatorsAward value
Imaging of microvascular dysfunction and cerebrovascular inflammation in vascular dementia Stuart Allan, Herve Boutin, Laura Parkes, Michael Harte, Adrian Parry-Jones, Tim Burnett, Ben Dickie £11,800

Strategic awards in precision medicine

Strategic awards to support our growing strengths in precision medicine (that is the identification, and exploitation of heterogeneity in human disease), to pump-prime major cutting-edge external applications.

Application deadline: CLOSED

Successful applications in 2014/15:

TitlePrincipal InvestigatorsAward value
Gene expression heterogeneity in ovarian cancer Stephen Taylor, Gordon Jayson £13,000
Identifying novel predictors of response to rituximab in patients with SLE John Reynolds, Emily Sutton, Tony Whetton, Anne Barton, Ian Bruce £14,500
Identification of biomarkers in synovial fluid for a conclusive diagnosis of periprosthetic infection in arthroplasty patients Tony Freemont, Tony Whetton £15,000
Developing a plasma-based biomarker for the early identification and stratification of Alzheimer’s disease Nigel Hooper, Kate Kellett, Tony Whetton, Andrew Pierce, Andrew Williamson £15,000
Developing a prediction algorithm for treatment response in rheumatoid arthritis including genetic and immunological profiles Sebastien Viatte, Ben Mulhearn, Tracy Hussell, Anne Barton £14,960

Research consortia

Awards to pump-prime new ideas to address the most important biomedical problems, through collaboration between groups of principal investigators with distinctive skills, for major external funding.

Application deadline: CLOSED

Successful applications in 2014/15:

 Title Principal Investigators Award  Value
Developing an analytic tool to identify depressive rumination during sleep Penny Lewis, Douglas Kell, Gavin Brown, Ian Anderson £49,912
Development of next-generation integrin antagonists to treat fibrosis Richard Bryce, Mark Travis, Karen Piper Hanley, Thomas Jowitt, Paul Mould, Roger Whitehead, Martin Humphries £49,771
Time-resolved analysis of stem cell responses to changes in substrate stiffness Joe Swift, Stephen Richardson, Lu Shin Wong £49,499
Human rhinovirus evolutionary dynamics and escape mechanisms as a novel target for asthma intervention strategies Nikolaos Papadopoulos, David Robertson, Simon Lovell, Angela Simpson £49,693
AxonGraft - Co-electrospun Biomimetic Grafts for Axonal Regeneration Geoff Parker, Fenglei Zhou, Julie Gough £49,678
Accelerating translation of novel diagnostics into clinic: peptide-oligonucleotide hydrogels for detection of circulating miRNA biomarkers in plasma and serum Elena Bichenkova, Aline Miller, Michela Garofalo, Constantinos Demonacos, Caroline Dive £50,000
Graphene based affinity sensors Neil Dixon, Dean Jackson, Mohamed Missous, Max Migliorato £44,000
A systems-level approach towards dissecting the pathogenesis of cleft lip and palate Mike Dixon, Magnus Rattray, Stephen Eyre, E Mangold (Uni of Bonn) £48,576
Dynamic pulsing of polarity kinase aPKC in human breast carcinoma: a novel therapeutic route? Nancy Papalopulu, Gillian Farnie, Rob Clarke, Sacha Howell £45,322
Nanoparticle-mediated silencing of endothelial adhesion junctions to favour systemic delivery of stem cells. A pilot study. Giulio Cossu and Nicola Tirelli £28,000
Establishment of biomarkers of toxic side effects caused by immune checkpoint inhibition therapy in cancer Tracy Hussell, Tim Illidge, John Radford, Andrew MacDonald, Joanne Konkel, John Grainger, Amy Saunders £23,616
Realizing precision medicine: molecular and phenotypic heterogeneity in ovarian cancer Stephen Taylor, Richard Edmonson, Gordon Jayson, Andrew Clamp, Andy Hayes, Leo Zeef, Charles Swanton (UCL) £49,658

Bridging support

To provide bridging support for key research staff in the area of biomedical research. This scheme funded proposals from any FBMH academic member of staff (including externally funded Fellows). Funds of up to £15k were available per application. 

Application deadline: CLOSED

Successful Bridging Support applications in 2014/15:

 Supervisor  PDRA   Award Value
Dave Thornton Eamon Dubaissi £13,518
Hugh Piggins Alun Hughes £14,338
Andreas Prokop Andre Voelzmann £6,072
Martin Baron Hideyuki Shimizu £14,862
Simon Luckman Nic Nunn £6,990
Martin Baron Marian Wilkin £11,722
Janine Lamb/Hector Chinoy Simon Rothwell £9,553
Richard Baines Carlo Giachello £14,484
Neil Dixon Samantha Halliwell £3,546
Andrew Chamberlain Lidija McKnight £12,831
Ian Roberts Eric Miller £11,780
Emmanuel Pinteaux Raymond Wong £14,258
Simon Lovell Shaun Kandathil £3,410
Simon Turner Manoj Kumar £14,155
Sue Kimber Ioannis Bantounas £7,828
Chris Knight Rok Krašovec £11,487
Sue Kimber Ioannis Bantounas £7,828
Philip Woodman Lydia Wunderley £12,606
Tony Day Jenny Scott £3,451

Collaborative research visits

To support short-term research visits (national or international) to establish/advance major collaborations in biomedical research. This scheme was open to all principal investigators (PIs) in the former FLS and FMHS (now FBMH) working on biomedical research projects. The scheme supported PI or post-doc visits to collaborators to advance their research. Funds of up to £2.5k were available per application.

Application deadline: CLOSED

Successful Collaborative Research Visit applications in 2014/15:

SupervisorAward Value
Jason Bruce £2,500
David Brough & Jack Rivers-Auty £1,985
Mark Humphries & Javier Caballero £660
Jules Schneider & Penny Lewis £615
Sarah Woolner & Georgina Stooke-Vaughan  £2,000
Catherine Lawrence & Michael Haley £2,000
Simon Anderson £2,492
Deborah Talmi £1,000
Kathy Hentges £409
Fenglei Zhou £2,200
Shane Herbert & Guilherme Costa £2,000
Fenglei Zhou  £2,200
Jean-Marc Schwartz £2,300

Research training opportunities

To support training opportunities on essential new techniques and capabilities. This scheme was open to all principal investigator (PIs) in FBMH working on biomedical research projects to attend high-level external training courses that offer the very latest research approaches.

The scheme supported PI or post-doc training opportunities visits. Funds of up to £2.5k were available per application.

Application deadline: CLOSED

Successful Researcher Training applications in 2014/15:

ResearcherAward Value
Gloria Lopez Castejon £2,300
Javier Caballero (Mark Humphries) £2,200
Abhinav Singh (Mark Humphries) £1,900
Georgina Stooke-Vaughan (Sarah Woolner) £515
Alex Mironov £1,400
Tim Eyes (Jeremy Derrick) £2,500
Nina Milosavljevic (Rob Lucas) £2,500
Silke Conen (Peter Talbot) £758.90

Public engagement

To support innovative projects in the areas of biomedical research. The scheme was open to staff and postgraduate students across the University for public engagement and outreach projects around the general theme of biomedical research and health, but must have been led by an academic member of staff in FBMH. Projects involving colleagues in FEPS or Humanities were encouraged. 

Application deadline: CLOSED

Successful Public Engagement applications 2017-2019 

Title

Lead Applicant

Scheme

Amount

Year

Have You Heard?

Kirsty McIntyre*(lead applicant), Mike Daniels, Katie Walwyn-Brown, Donna Littlewood, Jack Barton, Aidan Rooney

Emerging

£500

2017-2018

Broken Brain Games

Catriona Cunningham

Emerging

£215

2017-2018

A Day in the Life of Data - an immersive role-playing festival game

Sarah Fox, Mary Tully

Established

£3,000

2017-2018

Look Harder: Thinking Differently

Helena Tomlin, Helen Young

Established

£2,000

2017-2018

Pregnancy complications and Maternal & Fetal Health Research Centre (MFHRC) art workshops and exhibition

Michelle Desforges

Established

£3,000

2017-2018

The MixLab

Bella Starling

Established

£2,550

2017-2018

Psoriasis Shout Out: The People Behind the Research film

Chris Griffiths, Susie Moschogianis, Leah Holmes, Annie Keane, Emily Robinson

Established

£3,000

2017-2018

24 Hour Research All-nighter

David Ray, Andrew Loudon, David Bechtold, Qing-Jun Meng, Julie Gibbs, Magnus Rattray, Leah Holmes, Annie Keane, Emily Robinson

Established

£3,000

2017-2018

Royal Society courses

Kelly Rushton

Professional Development

£550

2017-2018

Technology of Participation / participatory techniques courses

Bentley Crudgington

Professional Development

£1,070

2017-2018

Thinking out of the Box

Carmen F. Ionita

Emerging

£204

2017-2018

Communicating Immunological Research on the Isle of May

Iris Mair

Emerging

£485

2017-2018

Empowering children to strengthen families: A film of a family intervention in Panama directed by children

Dawn Edge, Anilena Mejia

Established

£2,500

2017-2018

Public Engagement Evaluation Course

Dee-ann Johnson

Professional Development

£199

2017-2018

Sensory Theatre Labyrinth - 2 day course

Carmen F. Ionita

Professional Development

£300

2017-2018

Cloudy Ambassadors

Anna Beukenhorst

Emerging

£500

2018-2019

Manchester Neuroimaging: Imaging the Brain in Action!

Elizabeth McManus

Emerging

£473

2018-2019

Healthy dietary change to reduce greenhouse gas emissions from food

John Mclaughlin

Established

£3,000

2018-2019

PE career progression with Engage Academy

Emma Nichols

Professional

£1,740

2018-2019

  

Successful Public Engagement applications in 2014/15:

  Title  Principal InvestigatorsAward Value
The Art of Ageing Tony Day, Andrew Gilmore & Christoph Ballestrem £5,000
Giving Voice Elaine Lockton & Jenna Ashton £5,000
Reassembling the Self Jo Neill £4,980
Building Bridges: creating partnerships between autistic and research communities Emma Gowen, Anat Greenstein & Daniel Poole £5,000
Brain Attack Stuart Allan & Pippa Tyrrell £1,900
Understanding Health Research Kathryn Abel, Tony Morrison & Iracema Leroi £5,000
Caring for Children in Conflict Kim Cartwright, Aala El-Khani, Rachel Calam £5,000
Imitation, Dance and Understanding: Connecting Scientist and Women Asylum Seekers Together (WAST) Ellen Poliakoff, Emma Gowen & Judith Bek £4,990
Developing the Museum of Medicine and Health into a Platform for Public Engagement Carsten Timmermann, Kostas Arvanitis, Hawys Williams, Jenna Ashton, James Hopkins £4,955
From Coal Mining to Data Mining Will Dixon, Nicola Dale, Carsten Timmermann, Rupert Cox £3,450
Outbreak! Joanne Pennock & Jana Wendler

£5,000

Who Cares? Peter Bower, Katie Reed & Caroline Sanders £4,900
Science fiction for Science Understanding David Robertson, Ian Miller £5,000
Pain, the brain and a little bit of magic… Anthony Jones, Ben Mellor, Karina Lovell £5,000
Repair 2040 Mariarosa Mazza, Cyrill Bussy, Adam Reid, Stephen Richardson, Kirsty Heydon £5,000
Stroke: Stories of the Self Through Art and Science Stephanie Snow, Stuart Allan, Pippa Tyrrell, Chris Larkin and Joyce Booth (Stroke Association), Elisa Artesero (visual artist and curator) £4,995
Dementia Matters Iracema Leroi, Leah Holmes and Olivia O'Sullivan (Public Programmes Team) £4,050
  Penny Bee, Karian Lovell £4,700
The arts of neuroscience Nils Muhlert £1,500
Immersive data walkway, Cloudy with a Chance of Pain, Manchester Day Parade 2016 Will Dixon, David Schultz, Kingsley Purdham, Jer Thorp (Data Artist) £4,850
Soapbox Science Joanne Pennock, M Henson, A Hutcheson, A Watson, V Kinsley £1,530
Electro-Beats Alexander Holsgrove, Holly Shiels, Gina Galli £1,050
Seeing the Brain in Action Laura Parkes, Neils Muhler, Hamied Haroon, Sarah-Jane Clelland, Martin Turner £2,400
Resilience, Recovery and Happiness: Connecting Scientists and Victims of Torture Gillian Haddock, Kamelia Harris £4,950