| Acronym | Meaning |
| UCAS |
Universities and Colleges Admissions Service |
| UCEA |
Universities and Colleges Employers Association |
| UCIL |
University College for Interdisciplinary Learning |
| UCISA |
Universities and Colleges Information Systems Association |
| UF |
Unconditional Firm offer holder |
| UG |
Undergraduate |
| UHR |
Universities Human Resources |
| UKCES |
UK Commission for Employment and Skills |
| UKPMC |
UK PubMed Central |
| UKPRN |
UK Provider Reference Number |
| UKRI |
UK Research and Innovation |
| UKRLP |
UK Register of Learning Providers |
| UMI3 |
The University of Manchester's Intellectual Property Commercialisation Company |
| UMIC |
University of Manchester Innovation Centre Limited |
| ULC |
University Language Centre |
| UMBUG |
University of Manchester Bike User Group |
| UMIP |
University of Manchester Intellectual Property Limited |
| UML |
University of Manchester Libraries |
| UMPO |
UoM Physics Outreach |
| UMPSN |
University of Manchester Persian Staff Network |
| UMRI |
University of Manchester Research Institute |
| UMRUN |
University of Manchester Run Commute Group |
| UMSA |
University of Manchester Staff Association |
| UMSGS |
University of Manchester Staff Golfing Society |
| UMSS |
University of Manchester Superannuation Scheme |
| UMSU |
University of Manchester Students Union |
| UMW |
University of Manchester Worldwide |
| UMWB |
University of Manchester Worldwide Board |
| UNIAC |
Universities Internal Audit Consortium |
| UOA |
Unit of Assessment |
| UOM |
University of Manchester |
| UOMC |
University of Manchester Conferences Ltd |
| UoMCP |
University of Manchester Car Parks Limited |
| URG |
University Research Group |
| USS |
Universities Superannuation Scheme |
| UUK |
Universities UK |
| UURC |
University-Union Relations Committee |
| UVL |
UMIST Ventures Limited |